Multilocus Linkage Analysis of Affected Sib Pairs
نویسندگان
چکیده
منابع مشابه
Multilocus linkage analysis of affected sib pairs.
OBJECTIVE The conventional affected sib pair methods evaluate the linkage information at a locus by considering only marginal information. We describe a multilocus linkage method that uses both the marginal information and information derived from the possible interactions among several disease loci, thereby increasing the significance of loci with modest effects. METHODS Our method is based ...
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ژورنال
عنوان ژورنال: Human Heredity
سال: 2005
ISSN: 0001-5652,1423-0062
DOI: 10.1159/000091010